If you or a loved one have suffered organ failure, stroke, or even death after taking Oxbryta for sickle cell disease, you may be entitled to significant compensation. The law firm of Salenger, Sack, Kimmel & Bavaro, LLP is actively representing patients and families harmed by this recalled prescription drug.
We are investigating Oxbryta lawsuits nationwide to hold Pfizer accountable for failing to protect sickle cell patients from life-threatening side effects. Our team is ready to provide a free, private case review to help you explore your legal options.
Oxbryta is a sickle cell medication first developed by Global Blood Therapeutics and later acquired by Pfizer, Inc. Approved by the FDA in 2019 under an accelerated pathway, Oxbryta was designed to prevent red blood cells from sickling and reduce the risk of complications from sickle cell disease (SCD). In 2021, its approval was expanded for children as young as 4.
However, new post-marketing studies and clinical trial data revealed alarming results: patients taking Oxbryta experienced higher rates of VOCs and fatalities compared to the placebo group. This led to a voluntary recall of the drug in September 2024.
Oxbryta (voxelotor) is a prescription medication originally developed by Global Blood Therapeutics and later acquired by Pfizer. Approved by the FDA in 2019 through an accelerated pathway, it was marketed as a breakthrough for sickle cell disease (SCD) by preventing red blood cells from sickling, improving oxygen delivery, and reducing vaso-occlusive episodes.
By 2021, the FDA expanded approval to children as young as 4. But new clinical trial data revealed that Oxbryta could cause the very complications it was meant to prevent — including increased vaso-occlusive crises (VOCs), stroke, organ failure, and death.
On September 26, 2024, Pfizer issued a global recall of Oxbryta after alarming clinical trial results. The FDA confirmed that patients taking the drug experienced higher rates of VOCs, decreased oxygen delivery, and death compared to placebo.
Pfizer admitted that “the benefits no longer outweigh the risks” — a devastating admission for sickle cell patients who trusted the drug to improve their quality of life.
Reports and FDA safety data have linked Oxbryta side effects to severe, sometimes fatal health outcomes, including:
Organ Failure – Kidney, liver, and heart complications
Stroke – Blood clots causing brain injury or death
Vaso-Occlusive Crises (VOCs) – Painful, dangerous blockages in blood vessels
Fatal Complications – Sudden death linked to Oxbryta use
For sickle cell patients already battling a chronic illness, these risks are life-altering and devastating.
VOCs are painful, dangerous events in sickle cell patients where misshapen red blood cells block blood vessels, cutting off oxygen supply to vital organs.
VOC symptoms include:
Sudden pain in the chest, back, arms, or legs
Swelling in hands and feet (especially in children)
Fatigue or shortness of breath
Fever, stroke risk, or acute chest syndrome
June 16, 2025 — Wrongful Death Lawsuit Filed
A widow in Tennessee filed a wrongful death lawsuit in Northern District of California against Pfizer and Global Blood Therapeutics, alleging that her husband died from complications caused by Oxbryta, including increased VOCs and stroke. He began using Oxbryta in 2022, suffered a stroke in April 2024, and died in May 2024.
July 1, 2025 — Potential MDL in Discussion
Attorneys are monitoring whether Oxbryta lawsuits will be consolidated into a multidistrict litigation (MDL). While an MDL could streamline proceedings, some legal experts caution that it may reduce individual settlement values.
If you or a loved one has experienced complications from Oxbryta, don’t wait to seek legal help.
Contact Salenger, Sack, Kimmel & Bavaro today for a FREE consultation.
Call (800) 675-8556 or contact us online to get started.
You may be eligible to file an Oxbryta legal claim if:
You took Oxbryta for sickle cell disease and suffered organ failure, stroke, hospitalization, or death.
You are a surviving family member of someone who died while using Oxbryta.
You have medical records linking your injury to the drug.
If your case is successful, you may be entitled to recover:
Past & future medical expenses
Lost wages & reduced earning ability
Pain & suffering
Wrongful death damages
Punitive damages for corporate negligence
Our dangerous drug attorneys have decades of success in pharmaceutical litigation, including recalled medications and wrongful death claims. We partner with top medical experts, offer no upfront fees, and handle every case with personalized attention.
If you or a loved one experienced Oxbryta side effects, do not wait. Each state has a statute of limitations that limits how long you have to file an Oxbryta lawsuit.
📞 Call (800) 675-8556 or fill out our secure online form for your free consultation today. Let our Oxbryta injury lawyers fight for the justice and compensation you deserve.
Is Oxbryta still on the market?
No. Oxbryta was recalled in September 2024 and is no longer available.
Can I file on behalf of someone who died?
Yes. Wrongful death lawsuits are available to surviving spouses, children, or legal representatives.
Is this part of a class action?
Not yet. Oxbryta lawsuits are being filed individually, though future consolidation is possible.
Is there a time limit to file?
Yes. Each state has a statute of limitations, so act quickly to protect your claim.